TheraVet BIOCERA-VET GRANULES Instructions D'utilisation page 4

DISPOSAL
No special disposal measures are required for unopened prod-
ucts. Explanted or contaminated material must be disposed of
in accordance with the veterinary practices' standard disposal
procedure.
CONTRAINDICATIONS
BIOCERA-VET® GRANULES must not be used in case of:
 acute or chronic infections at the implantation site, e.g. os-
teomyelitis
 bone defects in the area of open epiphyseal plates
 patients with known calcium metabolism disorders, e.g.
hypercalcemia
BIOCERA-VET® GRANULES must be used only after carefully
weighing the risks and benefits in the case of:
 disorders of the bone metabolism
 endocrinopathies
 immunosuppressive therapy
 simultaneous therapy with medicines that influence bone
metabolism
 simultaneous treatment with resorption-inhibiting active
ingredients (particularly bisphosphonates, long term treat-
ments with NSAIDs – non-steroidal anti-inflammatory
drugs)
USE DURING PREGNANCY OR LACTATION
Studies in pregnant or nursing animals have not been con-
ducted.
USE IN PUPPIES
Studies in puppies have not been conducted. There are no
known reasons which would restrict use in young animals.
INTERACTIONS
If the patient is being treated at the same time with resorption-
inhibiting active substances (particularly bisphosphonates,
NSAIDs – non-steroidal anti-inflammatory drugs), it should be
assumed that the resorption of the implant material will be
slowed, an increased risk of subsequent bone breakage cannot
be excluded.
No additional interactions with other medical devices or medi-
cines are known, as long as they do not have a direct effect on
bone metabolism (see Contraindications).
BIOCERA-VET® GRANULES is a non-metallic, non-conducting
and non-magnetic scaffold and therefore is designated as MRI
safe.
PRECAUTIONS AND WARNINGS
The use of BIOCERA-VET® GRANULES is restricted to spe-
cialists who through their training are familiar with handling bone
substitute materials, with the appropriate surgical techniques as
well as with the treatment of bone defects.
Upon application of BIOCERA-VET® GRANULES, as with all
surgical interventions, surgery-related risks may occur, particu-
larly rejection reactions, pseudarthrosis, swelling, seroma and
hematoma formation, pain, and wound healing disorders. Sub-
sequent revision operations may become necessary.
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